BDBM35377 MLS000081820::N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-1,2-oxazole-5-carboxamide::N-[4-(4-methylphenyl)-2-thiazolyl]-5-isoxazolecarboxamide::N-[4-(p-tolyl)thiazol-2-yl]isoxazole-5-carboxamide::SMR000063580::cid_2999703

SMILES Cc1ccc(cc1)-c1csc(NC(=O)c2ccno2)n1

InChI Key InChIKey=WDTUFJHIGJTNSD-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 35377   

TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35377(MLS000081820 | N-[4-(4-methylphenyl)-1,3-thiazol-2...)
Affinity DataIC50:  3.90E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35377(MLS000081820 | N-[4-(4-methylphenyl)-1,3-thiazol-2...)
Affinity DataIC50:  4.98E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35377(MLS000081820 | N-[4-(4-methylphenyl)-1,3-thiazol-2...)
Affinity DataIC50:  4.98E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35377(MLS000081820 | N-[4-(4-methylphenyl)-1,3-thiazol-2...)
Affinity DataIC50:  4.97E+4nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay